CDK5R1 antibody (C-Term)

Catalog No. ABIN2779299

This Rabbit Polyclonal antibody specifically detects CDK5R1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig and Horse.

Quick Overview for CDK5R1 antibody (C-Term) (ABIN2779299)

Target: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5R1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK5R1 Antibody

Binding Specificity: C-Term

Purpose: Cdk5r1 Antibody - C-terminal region

Sequence: EAFWDRCLSV INLMSSKMLQ INADPHYFTQ VFSDLKNESG QEDKKRLLLG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Cdk5r1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30200-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK5R1

Target: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Alternative Name: Cdk5r1

Background:

Background Information: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Cdk5r1 is an activator of TPKII.

Gene Name: Cyclin-dependent kinase 5, regulatory subunit 1 (p35)

Alternative Symbols: p2, p3, p25, p35, Cdk5r, D11Bwg0379e

Protein Name: Cyclin-dependent kinase 5 activator 1

Molecular Weight: 34kDa

Gene ID: 12569

NCBI Accession: NP_034001

UniProt: P61809

Pathways: Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity