BAK1 antibody (N-Term)
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- Target See all BAK1 Antibodies
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BAK1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ASGQGPGPPR QECGEPALPS ASEEQVAQDT EEVFRSYVFY RHQQEQEAEG
- Predicted Reactivity
- Horse: 80%, Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against BAK1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product BAK1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 211 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Alternative Name
- BAK1 (BAK1 Products)
- Synonyms
- BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
- Background
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BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Alias Symbols: BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
Protein Interaction Partner: BCL2L2, BCL2A1, BCL2L1, BMH1, NFKBIB, HSD17B4, TOMM7, ABCB10, TOMM40, TP53, BAX, MCL1, UBC, DBN1, ARHGDIA, MFN1, BCL2L10, VDAC1, ERN1, BID, BAK1, VDAC2, BCL2, HSPD1, FRYL, SRRM2, MYCBP2, AKAP13, ACTR2, KRT31, FBL, DFFA,
Protein Size: 211 - Molecular Weight
- 23 kDa
- Gene ID
- 578
- NCBI Accession
- NM_001188, NP_001179
- UniProt
- Q16611
- Pathways
- Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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