MEFV antibody (N-Term)

Catalog No. ABIN2779421

This Rabbit Polyclonal antibody specifically detects MEFV in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Dog, Rabbit, Cow and Guinea Pig.

Quick Overview for MEFV antibody (N-Term) (ABIN2779421)

Target: MEFV (Mediterranean Fever (MEFV))

Reactivity: Human, Mouse, Rat, Horse, Dog, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEFV antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEFV Antibody

Binding Specificity: N-Term

Purpose: MEFV Antibody - N-terminal region

Sequence: TPSDHLLSTL EELVPYDFEK FKFKLQNTSV QKEHSRIPRS QIQRARPVKM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MEFV. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32016-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEFV

Target: MEFV (Mediterranean Fever (MEFV))

Alternative Name: MEFV

Background:

Background Information: MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors.

Gene Name: Mediterranean fever

Alternative Symbols: FMF, MEF, PAAND, TRIM20

Protein Name: Pyrin

Molecular Weight: 86kDa

Gene ID: 4210

NCBI Accession: NP_000234

UniProt: O15553

Pathways: Positive Regulation of Endopeptidase Activity