PAX4 antibody (Paired Box 4) (Middle Region)

Details for Product anti-PAX4 Antibody No. ABIN2779444
Antigen
Epitope
Middle Region
6
4
2
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
60
23
10
2
2
2
2
1
1
1
1
Host
Rabbit
37
16
7
Clonality
Polyclonal
Conjugate
This PAX4 antibody is un-conjugated
3
2
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
52
30
11
6
4
3
2
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PAX4
Blocking Peptide Blocking peptide for this product available: ABIN981387
Sequence RTIFSPSQAE ALEKEFQRGQ YPDSVARGKL ATATSLPEDT VRVWFSNRRA
Specificity 100 % homologous to all 3 isoforms (38, 30, 37 kDa).
Predicted Reactivity Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
Characteristics This is a rabbit polyclonal antibody against PAX4. It was validated on Western Blot.
Purification Affinity Purified
Antigen
Alternative Name PAX4 (PAX4 Antibody Abstract)
Background PAX4 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing .- cells.
Alias Symbols: KPD, MGC129960, MODY9
Protein Interaction Partner: GMCL1,
Protein Size: 343
Molecular Weight 37 kDa
Gene ID 5078
NCBI Accession NM_006193, NP_006184
UniProt O43316
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 343 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Paired Box 4 (PAX4) (Middle Region) antibody (ABIN2779444) Host: Rabbit Target Name: PAX4 Sample Type: Human Fetal Lung Antibody Dilution:...
Image no. 2 for anti-Paired Box 4 (PAX4) (Middle Region) antibody (ABIN2779444) Host: Rabbit Target Name: PAX4 Sample Type: COLO205 Antibody Dilution: 1.0ug/m...
Image no. 3 for anti-Paired Box 4 (PAX4) (Middle Region) antibody (ABIN2779444) Host: Rat Target Name: PAX4 Sample Tissue: Rat Brain Antibody Dilution: 1ug/ml
Image no. 4 for anti-Paired Box 4 (PAX4) (Middle Region) antibody (ABIN2779444) Host: Rabbit Target Name: PAX4 Sample Type: OVCAR-3 Antibody Dilution: 1.0ug/m...
Image no. 5 for anti-Paired Box 4 (PAX4) (Middle Region) antibody (ABIN2779444) WB Suggested Anti-PAX4 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat ce...
Image no. 6 for anti-Paired Box 4 (PAX4) (Middle Region) antibody (ABIN2779444) Host: Rabbit Target Name: PAX4 Sample Tissue: Human NCI-H226 Antibody Dilution:...
Product cited in: Zhang, Smyrk, Oliveira, Lohse, Zhang, Johnson, Lloyd: "KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers." in: The American journal of surgical pathology, Vol. 33, Issue 10, pp. 1562-9, 2010 (PubMed).