MMP19 antibody (N-Term)

Catalog No. ABIN2779559

The Rabbit Polyclonal anti-MMP19 antibody is suitable to detect MMP19 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Rabbit and Pig. It has been validated for WB and IHC.

Quick Overview for MMP19 antibody (N-Term) (ABIN2779559)

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MMP19 Antibody

Binding Specificity: N-Term

Purpose: MMP19 Antibody - N-terminal region

Sequence: ALRAFQEASE LPVSGQLDDA TRARMRQPRC GLEDPFNQKT LKYLLLGRWR

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MMP19. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP19

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104927

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMP19

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Alternative Name: MMP19

Background:

Background Information: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP-19 has not been determined. This gene corresponding to this protein was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19). Multiple transcript variants encoding distict isoforms have been identified for this gene.

Gene Name: Matrix metallopeptidase 19

Alternative Symbols: CODA, MMP18, RASI-1

Protein Name: Matrix metalloproteinase-19

Molecular Weight: 56kDa

Gene ID: 4327

NCBI Accession: NP_002420

UniProt: Q99542