AES antibody (N-Term)

Catalog No. ABIN2779564

Product Details anti-AES Antibody

Target: AES (Amino-terminal Enhancer of Split (AES))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AES antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QSRHSGSSHL PQQLKFTTSD SCDRIKDEFQ LLQAQYHSLK LECDKLASEK

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Aes. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Aes

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 197 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AES

Target: AES (Amino-terminal Enhancer of Split (AES))

Alternative Name: Aes (AES Products)

Synonyms: AES-1 antibody, AES-2 antibody, ESP1 antibody, GRG antibody, GRG5 antibody, TLE5 antibody, AL024115 antibody, Esp1 antibody, Grg antibody, Grg-5 antibody, Grg5 antibody, Tle5 antibody, zgc:64216 antibody, aes-1 antibody, aes-2 antibody, esp1 antibody, grg antibody, grg5 antibody, tle5 antibody, xgrg-5 antibody, AES antibody, amino-terminal enhancer of split antibody, amino-terminal enhancer of split S homeolog antibody, AES antibody, Aes antibody, aes antibody, aes.S antibody

Background: Aes acts as dominant repressor towards other family members. Aes inhibits NF-kappa-B-regulated gene expressionand may be required for the initiation and maintenance of the differentiated state .
Alias Symbols: AL024115, Grg, Grg5
Protein Interaction Partner: Tle1, Hdac3, Tle4, Pou2f1, Msx1, Aes, Six6, Six3, Hmgb1,
Protein Size: 197

Molecular Weight: 22 kDa

Gene ID: 14797

NCBI Accession: NM_010347, NP_034477

UniProt: P63002

Pathways: WNT Signaling, SARS-CoV-2 Protein Interactome