TLE3 antibody (N-Term)

Catalog No. ABIN2779589

The Rabbit Polyclonal anti-TLE3 antibody (ABIN2779589) specifically detects TLE3 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse and Pig samples.

Quick Overview for TLE3 antibody (N-Term) (ABIN2779589)

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TLE3 Antibody

Binding Specificity: N-Term

Purpose: TLE3 Antibody - N-terminal region

Sequence: GSSSGLLALG ALGSQAHLTV KDEKNHHELD HRERESSANN SVSPSESLRA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TLE3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32362-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLE3

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Alternative Name: TLE3

Background:

Background Information: The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.

Gene Name: Transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)

Alternative Symbols: ESG, ESG3, GRG3, HsT18976

Protein Name: Transducin-like enhancer protein 3

Molecular Weight: 83kDa

Gene ID: 7090

NCBI Accession: NP_005069

UniProt: Q04726

Pathways: SARS-CoV-2 Protein Interactome