T-Box 19 (TBX19) (Middle Region) antibody Primary Antibody
TBX19 Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat WB Host: Rabbit Polyclonal
Catalog No. ABIN2779591
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- Binding Specificity
- Middle Region
- Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
- Western Blotting (WB)
- Blocking Peptide
- Blocking peptide for this product available: ABIN984832
- IKYNPFAKAF LDAKERNHLR DVPEAISESQ HVTYSHLGGW IFSNPDGVCT
- Predicted Reactivity
- Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 77%
- This is a rabbit polyclonal antibody against TBX19. It was validated on Western Blot using a cell lysate as a positive control.
- Affinity Purified
- The immunogen is a synthetic peptide directed towards the middle region of human TBX19
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
Antigen size: 448 AA
- For Research Use only
- Lot specific
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Alternative Name
- TBX19 (TBX19 Antibody Abstract)
- TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ26302, FLJ34543, TBS 19, TBS19, TPIT, dJ747L4.1
Protein Interaction Partner: NR5A1,
Protein Size: 448
- Molecular Weight
- 48 kDa
- Gene ID
- NCBI Accession
- NM_005149, NP_005140
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