T-Box 19 antibody

Catalog No. ABIN6945138

Product Details anti-T-Box 19 Antibody

Target: T-Box 19 (TBX19)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This T-Box 19 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human TBXT aa 200-400.

Clone: 1F11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IP(1-2 μg)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for T-Box 19

Target: T-Box 19 (TBX19)

Alternative Name: TBXT (TBX19 Products)

Synonyms: TBX19 antibody, TBS19 antibody, TPIT antibody, dJ747L4.1 antibody, CH-TBXT antibody, TBXT antibody, AU019250 antibody, D1Ertd754e antibody, Tpit antibody, T-box 19 antibody, TBX19 antibody, Tbx19 antibody

Background:

Synonyms: T-box transcription factor T, TBXT, Brachyury protein

Background: TBXTis an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.

Gene ID: 6862

UniProt: O15178