PAX7 antibody (N-Term)

Catalog No. ABIN2779614

The Rabbit Polyclonal anti-PAX7 antibody is suitable to detect PAX7 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit and Horse. It has been validated for WB.

Quick Overview for PAX7 antibody (N-Term) (ABIN2779614)

Target: PAX7 (Paired Box 7 (PAX7))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAX7 Antibody

Binding Specificity: N-Term

Purpose: PAX7 Antibody - N-terminal region

Sequence: CDRSTVPSGL VSSISRVLRI KFGKKEEEDE ADKKEDDGEK KAKHSIDGIL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 75%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PAX7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAX7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8107550

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Alternative Name: PAX7

Background:

Background Information: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown. This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Gene Name: Paired box 7

Alternative Symbols: HUP1, RMS2, PAX7B, MYOSCO

Protein Name: Paired box protein Pax-7

Molecular Weight: 57kDa

Gene ID: 5081

NCBI Accession: NP_002575

UniProt: P23759