CTBP1 antibody (N-Term)

Catalog No. ABIN2779663

The Rabbit Polyclonal anti-CTBP1 antibody is suitable to detect CTBP1 in samples from Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio) and Rabbit. It has been validated for WB and IHC.

Quick Overview for CTBP1 antibody (N-Term) (ABIN2779663)

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CTBP1 Antibody

Binding Specificity: N-Term

Purpose: CTBP1 Antibody - N-terminal region

Sequence: TREDLEKFKA LRIIVRIGSG FDNIDIKSAG DLGIAVCNVP AASVEETADS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CTBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTBP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32469-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: CTBP1

Background:

Background Information: CTBP1 binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Gene Name: C-terminal binding protein 1

Alternative Symbols: BARS, HADDTS

Protein Name: C-terminal-binding protein 1

Molecular Weight: 46kDa

Gene ID: 1487

NCBI Accession: NP_001012632

UniProt: Q7Z2Q5

Pathways: Retinoic Acid Receptor Signaling Pathway