CIC antibody (N-Term)

Catalog No. ABIN2779683

There is 1 publication for this product available. The Rabbit Polyclonal anti-CIC antibody is suitable to detect CIC in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB and IHC.

Quick Overview for CIC antibody (N-Term) (ABIN2779683)

Target: CIC (Capicua Homolog (CIC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CIC Antibody

Binding Specificity: N-Term

Purpose: CIC Antibody - N-terminal region

Sequence: PSQPDPSVQP SEAQQPASHP VASNQSKEPA ESAAVAHERP PGGTGSADPE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CIon Channel. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CIC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32498-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CIC antibody (ABIN2779683)

Lee, Chan, Cheung, Cheng, Appleby, Orme, Scotting: "CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons." in: Brain research. Molecular brain research, Vol. 106, Issue 1-2, pp. 151-6, (2002) (PubMed).

Target Details for CIC

Target: CIC (Capicua Homolog (CIC))

Alternative Name: CIC

Background:

Background Information: CIon Channel represents a new subfamily of the HMG-box superfamily. Expression of the Cic gene is predominantly restricted to immature granule cells in the cerebellum, hippocampus and olfactory bulb in the CNS

Gene Name: Capicua homolog (Drosophila)

Alternative Symbols: MRD45

Protein Name: Protein capicua homolog

Molecular Weight: 164kDa

Gene ID: 23152

NCBI Accession: NP_055940

UniProt: Q96RK0