APP antibody (C-Term)

Catalog No. ABIN616902

The Rabbit Polyclonal anti-APP antibody (ABIN616902) specifically detects APP in WB and IHC. The antibody is reactive with Mouse and Rat samples.

Quick Overview for APP antibody (C-Term) (ABIN616902)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-APP Antibody

Binding Specificity: C-Term

Sequence: EVKMDAEFGH DSGFEVRHQK LVFFAEDVGS NKGAIIGLMV GGVVIATVIV

Predicted Reactivity: Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against App. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human App

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 733 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: App

Background: The function of App remains unknown.
Alias Symbols: Ag, Abpp, Adap, Cvap, Abeta, betaApp, AL024401, E030013M08Rik, App
Protein Interaction Partner: Ranbp9, Cpeb1, Bace1, Snca, Prnp, Gga1, Stub1, Ubc, Kif1a, Mme, Mapk8ip2, Mapk8ip1, Dab1,
Protein Size: 733

Molecular Weight: 90 kDa

Gene ID: 11820

NCBI Accession: NM_001198825, NP_001185754

UniProt: P12023

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour