MXI1 antibody (N-Term)

Catalog No. ABIN2779814

This Rabbit Polyclonal antibody specifically detects MXI1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Pig.

Quick Overview for MXI1 antibody (N-Term) (ABIN2779814)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXI1 Antibody

Binding Specificity: N-Term

Sequence: KEARCEGAGL VPVAPPAMPP AAAAPQPPAQ PEEPAGAKPR CPFSDIFNTS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 86%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Mxi1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Mxi1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 295 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Alternative Name: Mxi1

Background: This gene encodes a protein containing a helix-loop-helix domain characteristic of transcription factors, which allows heterodimerization and sequence-specific DNA binding. The encoded protein is related to a family of Myc/Max/Mad proteins that are involved in the regulation of several cellular processes. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate Myc function. Three alternatively spliced transcripts encoding different isoforms have been described.
Alias Symbols: ENSMUSG00000067085, Gm10197, Mad2, bHLHc11
Protein Interaction Partner: Smad9, Smad5, Smad1, Smarca5, Max, Smc3,
Protein Size: 295

Molecular Weight: 33 kDa

Gene ID: 17859

NCBI Accession: NM_001008542, NP_001008542

UniProt: Q3U3X2

Pathways: Maintenance of Protein Location