IRF1 antibody (C-Term)
Quick Overview for IRF1 antibody (C-Term) (ABIN2779860)
Target
See all IRF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- HIDGKGYLLN EPGTQLSSVY GDFSCKEEPE IDSPRGDIGI GIQHVFTEMK
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Predicted Reactivity
- Cow: 90%, Dog: 80%, Guinea Pig: 86%, Human: 93%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Sheep: 90%
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Characteristics
- This is a rabbit polyclonal antibody against Irf1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 329 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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Alternative Name
- Irf1
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Background
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Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Irf1 acts as a tumor suppressor.
Alias Symbols: AU020929, Irf-1
Protein Interaction Partner: Ubc, Sumo1, Ube2i, Pias3, Tbk1, Polr2a,
Protein Size: 329 -
Molecular Weight
- 37 kDa
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Gene ID
- 16362
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NCBI Accession
- NM_008390, NP_032416
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UniProt
- P15314
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Pathways
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
Target
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