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IRF1 antibody (C-Term)

This anti-IRF1 antibody is a Rabbit Polyclonal antibody detecting IRF1 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig and Sheep.
Catalog No. ABIN2779860

Quick Overview for IRF1 antibody (C-Term) (ABIN2779860)

Target

See all IRF1 Antibodies
IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivity

  • 86
  • 58
  • 35
  • 8
  • 8
  • 7
  • 7
  • 6
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Sheep

Host

  • 93
  • 7
  • 1
  • 1
Rabbit

Clonality

  • 85
  • 17
Polyclonal

Conjugate

  • 53
  • 12
  • 9
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IRF1 antibody is un-conjugated

Application

  • 86
  • 25
  • 23
  • 18
  • 15
  • 12
  • 9
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 8
    • 8
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequence

    HIDGKGYLLN EPGTQLSSVY GDFSCKEEPE IDSPRGDIGI GIQHVFTEMK

    Predicted Reactivity

    Cow: 90%, Dog: 80%, Guinea Pig: 86%, Human: 93%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Sheep: 90%

    Characteristics

    This is a rabbit polyclonal antibody against Irf1. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide corresponding to a region of Mouse
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 329 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    IRF1 (Interferon Regulatory Factor 1 (IRF1))

    Alternative Name

    Irf1

    Background

    Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Irf1 acts as a tumor suppressor.
    Alias Symbols: AU020929, Irf-1
    Protein Interaction Partner: Ubc, Sumo1, Ube2i, Pias3, Tbk1, Polr2a,
    Protein Size: 329

    Molecular Weight

    37 kDa

    Gene ID

    16362

    NCBI Accession

    NM_008390, NP_032416

    UniProt

    P15314

    Pathways

    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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