NK2 Homeobox 3 antibody (Middle Region)

Catalog No. ABIN2779878

Product Details anti-NK2 Homeobox 3 Antibody

Target: NK2 Homeobox 3 (NKX2-3)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NK2 Homeobox 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GTHAPPPPPR RVAVPVLVRD GKPCVTPSAQ TYGSPYGVGA GAYSYNSFPA

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Human: 77%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NKX2-3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse NKX2-3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 362 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NK2 Homeobox 3 antibody (ABIN2779878)

Tarlinton, Light, Metcalf, Harvey, Robb: "Architectural defects in the spleens of Nkx2-3-deficient mice are intrinsic and associated with defects in both B cell maturation and T cell-dependent immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 8, pp. 4002-10, (2003) (PubMed).

Target Details for NK2 Homeobox 3

Target: NK2 Homeobox 3 (NKX2-3)

Alternative Name: NKX2-3 (NKX2-3 Products)

Synonyms: CSX3 antibody, NK2.3 antibody, NKX2.3 antibody, NKX2C antibody, NKX4-3 antibody, Nkx-2.3 antibody, Nkx2.3 antibody, tinman antibody, CNKX-2.3 antibody, NK2 homeobox 3 antibody, NK2 transcription factor related, locus 3 antibody, NKX2-3 antibody, Nkx2-3 antibody

Background: NKX2C is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions.
Alias Symbols: Nkx2.3, tinman, Nkx-2.3
Protein Interaction Partner: Zfp263, Cdx1,
Protein Size: 362

Molecular Weight: 40 kDa

Gene ID: 18089

NCBI Accession: NM_008699, NP_032725

UniProt: P97334