ECSIT antibody (Middle Region)

Catalog No. ABIN2779984

The Rabbit Polyclonal anti-ECSIT antibody (ABIN2779984) specifically detects ECSIT in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig samples.

Quick Overview for ECSIT antibody (Middle Region) (ABIN2779984)

Target: ECSIT

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECSIT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ECSIT Antibody

Binding Specificity: Middle Region

Sequence: KVTVYQMSLP SDSTGMEDPT QPHIVGIQSP DQQAALARHN PSRPVFVEGP

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SITPEC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse SITPEC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 435 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ECSIT

Target: ECSIT

Alternative Name: SITPEC

Background: Sitpec functions as an essential component in two important signal transduction pathways and establishes a novel role for Ecsit as a cofactor for Smad proteins in the bone morphogenetic protein signaling pathway.
Alias Symbols: Sitpec
Protein Interaction Partner: Map3k1, Traf6, Irak1, SMURF1,
Protein Size: 435

Molecular Weight: 48 kDa

Gene ID: 26940

NCBI Accession: NM_012029, NP_036159

UniProt: Q9QZH6

Pathways: TLR Signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome