SRA1 antibody (N-Term)
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- Target See all SRA1 Antibodies
- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
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Binding Specificity
- N-Term
- Reactivity
- Human, Rat, Mouse, Cow, Guinea Pig, Horse, Dog, Rabbit, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SRA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MMRCPAGGAE VEMAELYVKP GNKERGWNDP PQFSYGLQTQ TGGPKRTPLT
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 93%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against Sra1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product SRA1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 220 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
- Alternative Name
- Sra1 (SRA1 Products)
- Synonyms
- SRA antibody, SRAP antibody, STRAA1 antibody, pp7684 antibody, AA959952 antibody, Sra antibody, Srap antibody, Straa1 antibody, Strra1 antibody, zgc:86613 antibody, steroid receptor RNA activator 1 antibody, steroid receptor RNA activator 1 S homeolog antibody, cytoplasmic FMR1 interacting protein 1 antibody, SRA1 antibody, Sra1 antibody, sra1 antibody, sra1.S antibody, CYFIP1 antibody
- Background
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Sra1 is a functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Sra1 also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2).Sra1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. Sra1 may play a role in tumorigenesis.
Alias Symbols: AA959952, SRA, STRAA1, Strra1, Sra, Srap, Straa1
Protein Interaction Partner: CFTR, Traf6, Pus1,
Protein Size: 220 - Molecular Weight
- 24 kDa
- Gene ID
- 24068
- NCBI Accession
- NM_025291, NP_079567
- UniProt
- Q80VJ2
- Pathways
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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