FUBP1 antibody (N-Term)

Catalog No. ABIN2780231

This Rabbit Polyclonal antibody specifically detects FUBP1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for FUBP1 antibody (N-Term) (ABIN2780231)

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FUBP1 Antibody

Binding Specificity: N-Term

Purpose: FUBP1 Antibody - N-terminal region

Sequence: IGKGGETIKQ LQERAGVKMV MIQDGPQNTG ADKPLRITGD PYKVQQAKEM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against FUBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUBP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100445

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-FUBP1 antibody (ABIN2780231)

Zheng, Shen, Hu, Roy, Yang, Wang, Zhang, King, Sergi, Liu, Cordat, Tang, Cao, Ali, Chen: "Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation." in: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 9, pp. 2645-57, (2016) (PubMed).

Target Details for FUBP1

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Alternative Name: FUBP1

Background:

Background Information: Far upstream element-binding protein activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. FUBP activity may be regulated by alternative splicing, translation efficiency, and posttranslational modification.

Gene Name: Far upstream element (FUSE) binding protein 1

Alternative Symbols: FBP, FUBP, hDH V

Protein Name: Far upstream element-binding protein 1

Molecular Weight: 68kDa

Gene ID: 8880

NCBI Accession: NP_003893

UniProt: Q96AE4