RELB antibody (N-Term)

Catalog No. ABIN2780295

The Rabbit Polyclonal anti-RELB antibody is suitable to detect RELB in samples from Human, Mouse, Rat, Dog and Cow. It has been validated for WB.

Quick Overview for RELB antibody (N-Term) (ABIN2780295)

Target: RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RELB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RELB Antibody

Binding Specificity: N-Term

Purpose: RELB Antibody - N-terminal region

Sequence: MPSRRAARES APELGALGSS DLSSLSLTVS RTTDELEIID EYIKENGFGL

Predicted Reactivity: Cow: 86%, Dog: 93%, Human: 93%, Mouse: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against RELB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse RELB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37870-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RELB

Target: RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

Alternative Name: RELB

Background:

Background Information: RelB is a member of the Rel/nuclear factor (NF)-kappa B family of transcription factors, defects in RelB affects antigen presenting cells and the formation of lymphoid organs. Targeted disruption of the Rel/NF-kappaB family members NF-kappaB2, encoding p100/p52, and RelB in mice results in anatomical defects of secondary lymphoid tissues.

Gene Name: Avian reticuloendotheliosis viral (v-rel) oncogene related B

Alternative Symbols: sh, shep

Protein Name: Transcription factor RelB

Molecular Weight: 61kDa

Gene ID: 19698

NCBI Accession: NP_033072

UniProt: Q04863

Pathways: NF-kappaB Signaling, RTK Signaling