PAX6 antibody (N-Term)

Catalog No. ABIN2780375

This anti-PAX6 antibody is a Rabbit Polyclonal antibody detecting PAX6 in WB. Suitable for Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Horse, Dog, Guinea Pig and Pig.

Quick Overview for PAX6 antibody (N-Term) (ABIN2780375)

Target: PAX6 (Paired Box 6 (PAX6))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Horse, Dog, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAX6 Antibody

Binding Specificity: N-Term

Sequence: LAHSGARPCD ISRILQTHAD AKVQVLDNQN VSNGCVSKIL GRYYETGSIR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PAX6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAX6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 436 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6

Background: PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA,
Alias Symbols: AN, AN2, MGDA, WAGR, D11S812E
Protein Interaction Partner: IPO13, Dlg4, NKIRAS2, Cacnb3, Pax6, Diap1, SMAD5, SMAD4, SMAD3, SMAD1, AR, HIPK2, SUMO1, SMARCA4, TP73, SHANK3, PBX1, VSX2, EN1, TRIM11, HOMER3, SIX3, INADL, EP300, SOX10, RGS3, DIAPH1, MAFG, RAX, DYNLL1, DLG1, CDX2, TBP, SOX3, MITF, HOXB1, SOX2, LHX2, TA
Protein Size: 436

Molecular Weight: 48 kDa

Gene ID: 5080

NCBI Accession: NM_001604, NP_001595

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis