MAZ antibody (N-Term)

Catalog No. ABIN2780422

This Rabbit Polyclonal antibody specifically detects MAZ in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat and Pig.It has been mentioned in 1 publication

Quick Overview for MAZ antibody (N-Term) (ABIN2780422)

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAZ Antibody

Binding Specificity: N-Term

Purpose: MAZ Antibody - N-terminal region

Sequence: FPVFPCTLLA PPFPVLGLDS RGVGGLMNSF PPPQGHAQNP LQVGAELQSR

Predicted Reactivity: Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAZ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAZ

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38146-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-MAZ antibody (ABIN2780422)

Smits, Wurdinger, van het Hof, Drexhage, Geerts, Wesseling, Noske, Vandertop, de Vries, Reijerkerk: "Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 6, pp. 2639-47, (2012) (PubMed).

Target Details for MAZ

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Alternative Name: MAZ

Background:

Background Information: MAZ may function as a transcription factor with dual roles in transcription initiation and termination.It binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.

Gene Name: MYC-associated zinc finger protein (purine-binding transcription factor)

Alternative Symbols: PUR1, ZF87, Pur-1, SAF-1, SAF-2, SAF-3, Zif87, ZNF801

Protein Name: Myc-associated zinc finger protein

Molecular Weight: 49 kDa

Gene ID: 4150

NCBI Accession: NP_002374

UniProt: P56270

Pathways: Chromatin Binding