NEUROD1 antibody (Middle Region)

Catalog No. ABIN2780434

The Rabbit Polyclonal anti-NEUROD1 antibody (ABIN2780434) specifically detects NEUROD1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Guinea Pig, Pig, Sheep and Zebrafish (Danio rerio) samples.

Quick Overview for NEUROD1 antibody (Middle Region) (ABIN2780434)

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Pig, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEUROD1 Antibody

Binding Specificity: Middle Region

Sequence: ATLAGAQSHG SIFSGTAAPR CEIPIDNIMS FDSHSHHERV MSAQLNAIFH

Predicted Reactivity: Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against NEUROD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NEUROD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 356 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Alternative Name: NEUROD1

Background: NeuroD1is a members of bHLH family that involves in neuroendocrine differentiation. This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BETA2, BHF-1, NEUROD, MODY6, bHLHa3
Protein Interaction Partner: DUSP3, SMARCA4, MAFA, EP300, TCF4, RREB1, PITX1, NEUROD1, HAP1, PDX1, CALM3, CALM1, CCND1, MAP3K10, HTT,
Protein Size: 356

Molecular Weight: 40 kDa

Gene ID: 4760

NCBI Accession: NM_002500, NP_002491

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis