Phospholipase D2 antibody (N-Term)

Catalog No. ABIN2780445

Product Details anti-Phospholipase D2 Antibody

Target: Phospholipase D2 (PLD2)

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Horse, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase D2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTATPESLFP TGDELDSSQL QMESDEVDTL KEGEDPADRM HPFLAIYELQ

Predicted Reactivity: Cow: 86%, Dog: 85%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Mouse: 75%, Rabbit: 86%, Rat: 75%

Characteristics: This is a rabbit polyclonal antibody against PLD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 933 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Phospholipase D2

Target: Phospholipase D2 (PLD2)

Alternative Name: PLD2 (PLD2 Products)

Synonyms: Pldc antibody, PLD2 antibody, phospholipase D2 antibody, PLD2 antibody, Pld2 antibody, pld2 antibody, CpipJ_CPIJ013122 antibody, VDBG_00892 antibody

Background: Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-14 AF033850.1 61-74 15-614 BC015033.1 1-600 615-1279 BC056871.1 549-1213 1280-1830 BC015033.1 1266-1816 1831-1995 BC056871.1 1765-1929 1996-3489 BC015033.1 1982-3475
Alias Symbols: -
Protein Interaction Partner: UBC, RPS6KB1, CUL3, AQP3, RPTOR, PEA15, PIP5K1A, STXBP1, DPYSL2, BIN1, MTOR, CAV1, AMPH, OPRM1, ALDOC, GM2A, PRKCD, PRKCA, PLCG1, LCK, GAPDH, FYN, EGFR, CSK, ALDOA, ARF1, ACTB, ACTN1, CAV2, SRC,
Protein Size: 933

Molecular Weight: 106 kDa

Gene ID: 5338

NCBI Accession: NM_002663, NP_002654

UniProt: O14939

Pathways: RTK Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling