ASCL2 antibody (C-Term)

Catalog No. ABIN2780652

The Rabbit Polyclonal anti-ASCL2 antibody is suitable to detect ASCL2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig and Pig. It has been validated for WB.

Quick Overview for ASCL2 antibody (C-Term) (ABIN2780652)

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASCL2 Antibody

Binding Specificity: C-Term

Sequence: RPQAVRPSAP RGPPGTTPVA ASPSRASSSP GRGGSSEPGS PRSAYSSDDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ASCL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ASCL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 193 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASCL2

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Alternative Name: ASCL2

Background: This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Alias Symbols: ASH2, HASH2, MASH2, bHLHa45
Protein Interaction Partner: EP300, APEX1, CALM3, CALM1, HCFC1, TUBB, KMT2C, NCOA6, TUBA4A, RBBP5,
Protein Size: 193

Molecular Weight: 20 kDa

Gene ID: 430

NCBI Accession: NM_005170, NP_005161

UniProt: Q99929

Pathways: Stem Cell Maintenance