TP53BP2 antibody (N-Term)

Catalog No. ABIN2780683

The Rabbit Polyclonal anti-TP53BP2 antibody (ABIN2780683) specifically detects TP53BP2 in WB. The antibody is reactive with Human, Mouse, Dog, Rat, Cow, Horse, Guinea Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for TP53BP2 antibody (N-Term) (ABIN2780683)

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Reactivity: Human, Mouse, Dog, Rat, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TP53BP2 Antibody

Binding Specificity: N-Term

Purpose: TP53BP2 Antibody - N-terminal region

Sequence: TLAELQEMAS RQQQQIEAQQ QLLATKEQRL KFLKQQDQRQ QQQVAEQEKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against TP53BP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TP53BP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115039

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Alternative Name: TP53BP2

Background:

Background Information: TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. TP53BP2 contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. TP53BP2 is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family.

Gene Name: Tumor protein p53 binding protein, 2

Alternative Symbols: BBP, 53BP2, ASPP2, P53BP2, PPP1R13A

Protein Name: Apoptosis-stimulating of p53 protein 2

Molecular Weight: 124kDa

Gene ID: 7159

NCBI Accession: NP_001026855

UniProt: Q13625