SIX Homeobox 1 antibody (Middle Region)

Catalog No. ABIN2780733

The Rabbit Polyclonal anti-SIX Homeobox 1 antibody (ABIN2780733) specifically detects SIX Homeobox 1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for SIX Homeobox 1 antibody (Middle Region) (ABIN2780733)

Target: SIX Homeobox 1 (SIX1)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIX Homeobox 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIX Homeobox 1 Antibody

Binding Specificity: Middle Region

Sequence: LQGNMGHARS SNYSLPGLTA SQPSHGLQTH QHQLQDSLLG PLTSSLVDLG

Predicted Reactivity: Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SIX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 284 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIX Homeobox 1

Target: SIX Homeobox 1 (SIX1)

Alternative Name: SIX1

Background: SIX1 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dom
Alias Symbols: BOS3, DFNA23, TIP39
Protein Interaction Partner: AES, VTN, FZR1, UBC, SKI, CCDC85B, DACH1, EYA3, EYA2, MDFI, EYA4, EYA1, SIX1, TLE1,
Protein Size: 284

Molecular Weight: 32 kDa

Gene ID: 6495

NCBI Accession: NM_005982, NP_005973

UniProt: Q15475

Pathways: Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development