SIX Homeobox 1 antibody (N-Term)

Catalog No. ABIN927733

Product Details anti-SIX Homeobox 1 Antibody

Target: SIX Homeobox 1 (SIX1)

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIX Homeobox 1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: SIX1 antibody was raised in rabbit using the N terminal of Six1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

SIX1 Blocking Peptide, catalog no. 33R-2703, is also available for use as a blocking control in assays to test for specificity of this SIX1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SIX Homeobox 1

Target: SIX Homeobox 1 (SIX1)

Alternative Name: SIX1 (SIX1 Products)

Synonyms: BOS3 antibody, DFNA23 antibody, TIP39 antibody, BB138287 antibody, six1b antibody, six2 antibody, zgc:92332 antibody, XSix1 antibody, six1 antibody, zgc:77345 antibody, SIX homeobox 1 antibody, sine oculis-related homeobox 1 antibody, SIX homeobox 1a antibody, SIX homeobox 1 L homeolog antibody, SIX homeobox 1b antibody, SIX1 antibody, Six1 antibody, six1a antibody, six1.L antibody, six1b antibody

Background: Six1 is a transcription factor that is involved in regulation of organogenesis. It seems to be required for development of kidney, muscle and inner ear and to be involved in later steps of myogenic differentiation. It may be involved in limb tendon and ligament development. It binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter. It is thought to be regulated by association with Dach and Eya proteins. Synonyms: Polyclonal Six1 antibody, Anti-Six1 antibody, sine oculis-related homeobox 1 homolog, Drosophila antibody, BB138287 antibody.

Pathways: Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development