DP1 antibody (N-Term)

Catalog No. ABIN2780829

Product Details anti-DP1 Antibody

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLSPGKGVVS LVAVHPSTVN TLGKQLLPKT FGQSNVNITQ QVVIGTPQRP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Tfdp1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 410 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DP1

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Alternative Name: Tfdp1 (TFDP1 Products)

Synonyms: tfdp1l antibody, wu:fb94b07 antibody, wu:fc52a06 antibody, zgc:55487 antibody, DP1 antibody, DRTF1 antibody, Dp-1 antibody, Dp1 antibody, Drtf1 antibody, TFDP1 antibody, dp-1 antibody, dp1 antibody, drtf1 antibody, tfdp1 antibody, tfdp1a antibody, transcription factor Dp-1, a antibody, transcription factor Dp-1 antibody, transcription factor Dp 1 antibody, transcription factor Dp-1 pseudogene antibody, transcription factor Dp-1 L homeolog antibody, tfdp1a antibody, TFDP1 antibody, Tfdp1 antibody, LOC465967 antibody, tfdp1.L antibody, tfdp1 antibody, PITG_20195 antibody, Tsp_02025 antibody, LOC100457325 antibody

Background: Tfdp1 can stimulate E2F-dependent transcription. Tfdp1 binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Alias Symbols: Dp1, Drtf1
Protein Interaction Partner: L3mbtl2, Sertad1, SERTAD2, E2f1, Rnf2, Epc1, E2F6,
Protein Size: 410

Molecular Weight: 45 kDa

Gene ID: 21781

NCBI Accession: NM_009361, NP_033387

UniProt: Q08639

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases