TRIM29 antibody (N-Term)

Catalog No. ABIN2780855

The Rabbit Polyclonal anti-TRIM29 antibody has been validated for WB. It is suitable to detect TRIM29 in samples from Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog and Rabbit.

Quick Overview for TRIM29 antibody (N-Term) (ABIN2780855)

Target: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM29 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM29 Antibody

Binding Specificity: N-Term

Sequence: EAADASRSNG SSPEARDARS PSGPSGSLEN GTKADGKDAK TTNGHGGEAA

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TRIM29. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM29

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 588 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM29

Target: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Alternative Name: TRIM29

Background: This protein belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATDC, FLJ36085
Protein Interaction Partner: GOLGA2, TRIM23, LZTS2, CEP70, CARD9, MAD1L1, TRIP6, TRIM29, SMAD9, KAT5, Tpr, Mis12, Cdk1, HDAC9, TAX1BP3, FBXL19, MED7, IKBKG, SP100, SNAPC1, SHOX2, POLR2E, POLR2D, PRICKLE3, HCLS1, GTF2E1, GATA1, DMRT1, PARP1, TRIM27, JAKMIP2, FBF1, CRACR2A, UBE2I, GCC1
Protein Size: 588

Molecular Weight: 66 kDa

Gene ID: 23650

NCBI Accession: NM_012101, NP_036233

UniProt: Q14134

Pathways: p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus