RERE antibody (N-Term)

Catalog No. ABIN2780857

The Rabbit Polyclonal anti-RERE antibody (ABIN2780857) specifically detects RERE in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Dog and Saccharomyces cerevisiae samples.

Quick Overview for RERE antibody (N-Term) (ABIN2780857)

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Dog, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RERE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RERE Antibody

Binding Specificity: N-Term

Purpose: RERE Antibody - N-terminal region

Sequence: MTADKDKDKD KEKDRDRDRD REREKRDKAR ESENSRPRRS CTLEGGAKNY

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%

Characteristics: This is a rabbit polyclonal antibody against RERE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RERE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38954-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RERE

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Alternative Name: RERE

Background:

Background Information: RERE is a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. RERE co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development.This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Arginine-glutamic acid dipeptide (RE) repeats

Alternative Symbols: ARG, ARP, DNB1, ATN1L, NEDBEH

Protein Name: Arginine-glutamic acid dipeptide repeats protein

Molecular Weight: 172kDa

Gene ID: 473

NCBI Accession: NP_036234

UniProt: Q9P2R6

Pathways: Protein targeting to Nucleus