RERE antibody (N-Term)

Catalog No. ABIN653912

There is 1 publication for this product available. The Rabbit Polyclonal anti-RERE antibody is suitable to detect RERE in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for RERE antibody (N-Term) (ABIN653912)

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RERE antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23369

Product Details anti-RERE Antibody

Binding Specificity: AA 383-409, N-Term

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RERE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-409 amino acids from the N-terminal region of human RERE.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-RERE antibody (ABIN653912)

Kumar, Duester: "Retinoic acid controls body axis extension by directly repressing Fgf8 transcription." in: Development (Cambridge, England), Vol. 141, Issue 15, pp. 2972-7, (2014) (PubMed).

Target Details for RERE

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Alternative Name: RERE

Background: RERE encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development.

Molecular Weight: 172424

Gene ID: 473

NCBI Accession: NP_001036146, NP_001036147, NP_036234

UniProt: Q9P2R6

Pathways: Protein targeting to Nucleus