NT5C antibody (C-Term)

Catalog No. ABIN2780936

The Rabbit Polyclonal anti-NT5C antibody (ABIN2780936) specifically detects NT5C in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for NT5C antibody (C-Term) (ABIN2780936)

Target: NT5C (5',3'-Nucleotidase, Cytosolic (NT5C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NT5C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NT5C Antibody

Binding Specificity: C-Term

Purpose: NT5C Antibody - C-terminal region

Sequence: QEETPSWEHI LFTCCHNRHL VLPPTRRRLL SWSDNWREIL DSKRGAAQRE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NT5C. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39112-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NT5C

Target: NT5C (5',3'-Nucleotidase, Cytosolic (NT5C))

Alternative Name: NT5C

Background:

Background Information: This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.

Gene Name: 5', 3'-nucleotidase, cytosolic

Alternative Symbols: DNT, cdN, DNT1, P5N2, PN-I, HEL74, PN-II, UMPH2, dNT-1

Protein Name: 5'(3')-deoxyribonucleotidase, cytosolic type

Molecular Weight: 23kDa

Gene ID: 30833

NCBI Accession: NP_055410

UniProt: Q8TCD5