CoREST antibody (REST Corepressor 1) (N-Term)

Details for Product anti-RCOR1 Antibody No. ABIN2780965, Supplier: Log in to see
Antigen
  • COREST
  • RCOR
  • 5730409O11
  • 6720480E22Rik
  • AU042633
  • D12Wsu95e
  • mKIAA0071
  • rcor1
  • xcoREST
  • RCOR1
  • im:6904264
  • si:dkey-46n18.7
  • zgc:158607
  • RGD1305743
  • REST corepressor 1
  • REST corepressor 1 L homeolog
  • RCOR1
  • Rcor1
  • rcor1.L
  • rcor1
Alternatives
anti-Human CoREST antibody for Immunocytochemistry
Epitope
N-Term
10
10
7
6
5
4
1
Reactivity
Human, Mouse (Murine), Zebrafish (Danio rerio)
62
11
5
4
3
3
3
2
2
1
Host
Rabbit
45
20
1
Clonality
Polyclonal
Conjugate
This CoREST antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
57
30
24
22
20
9
5
2
2
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human RCOR1
Sequence MVEKGPEVSG KRRGRNNAAA SASAAAASAA ASAACASPAA TAASGAAASS
Predicted Reactivity Human: 100%, Mouse: 100%, Zebrafish: 90%
Characteristics This is a rabbit polyclonal antibody against RCOR1. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Plasmids, Primers & others Plasmids, Primers & others CoREST products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name RCOR1 (RCOR1 Antibody Abstract)
Background RCOR1 is a functional corepressor required for regulation of neural-specific gene expression.The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.[supplied by OMIM].
Alias Symbols: COREST, KIAA0071, RCOR
Protein Interaction Partner: HDAC1, UBC, KDM1A, HDAC2, HDAC3, NPM1, MTA3, TP53BP1, NR2C1, TCF3, HMG20B, RCOR1, SNAI1, SUMO2, Dynll1, HIST3H3, TAL1, GFI1, GFI1B, MED28, OBFC1, SUB1, MED12, TRIP4, BCL3, ESCO2, SERPINH1, ZNF217, EMD, CTBP1, RL2, NR2E1, REST, HIST1H3A, SMARCE1, SMARCC2,
Protein Size: 482
Molecular Weight 53 kDa
Gene ID 23186
NCBI Accession NM_015156, NP_055971
UniProt Q9UKL0
Pathways Regulation of Hormone Metabolic Process, Chromatin Binding
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 482 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-REST Corepressor 1 (RCOR1) (N-Term) antibody (ABIN2780965) WB Suggested Anti-RCOR1 Antibody Titration: 1.25ug/ml Positive Control: Jurkat cel...
Immunohistochemistry (IHC) image for anti-REST Corepressor 1 (RCOR1) (N-Term) antibody (ABIN2780965) Human Lung
Immunohistochemistry (IHC) image for anti-REST Corepressor 1 (RCOR1) (N-Term) antibody (ABIN2780965) Rabbit Anti-RCOR1 antibody Paraffin Embedded Tissue: Human Lung cell Cell...
Product cited in: Packer, Xing, Harper, Jones, Davidson: "The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 53, pp. 14341-6, 2009 (PubMed).

Background publications Battaglioli, Andrés, Rose, Chenoweth, Rosenfeld, Anderson, Mandel: "REST repression of neuronal genes requires components of the hSWI.SNF complex." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 41038-45, 2002 (PubMed).

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