CoREST antibody (C-Term)

Catalog No. ABIN2780966

This Rabbit Polyclonal antibody specifically detects CoREST in WB. It exhibits reactivity toward Human, Mouse, Dog, Guinea Pig, Cow and Horse.

Quick Overview for CoREST antibody (C-Term) (ABIN2780966)

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Reactivity: Human, Mouse, Dog, Guinea Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CoREST antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CoREST Antibody

Binding Specificity: C-Term

Purpose: RCOR1 Antibody - C-terminal region

Sequence: DEVLQEWEAE HGKEETNGPS NQKPVKSPDN SIKMPEEEDE APVLDVRYAS

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Mouse: 79%

Characteristics: This is a rabbit polyclonal antibody against RCOR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RCOR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110325

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CoREST

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Alternative Name: RCOR1

Background:

Background Information: RCOR1 is a functional corepressor required for regulation of neural-specific gene expression.The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.[supplied by OMIM].

Gene Name: REST corepressor 1

Alternative Symbols: RCOR, COREST

Protein Name: REST corepressor 1

Molecular Weight: 53kDa

Gene ID: 23186

NCBI Accession: NP_055971

UniProt: Q9UKL0

Pathways: Regulation of Hormone Metabolic Process, Chromatin Binding