JMJD6 antibody (N-Term)

Catalog No. ABIN2780967

This Rabbit Polyclonal antibody specifically detects JMJD6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse and Guinea Pig.

Quick Overview for JMJD6 antibody (N-Term) (ABIN2780967)

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JMJD6 Antibody

Binding Specificity: N-Term

Purpose: JMJD6 Antibody - N-terminal region

Sequence: NHKSKKRIRE AKRSARPELK DSLDWTRHNY YESFSLSPAA VADNVERADA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against JMJD6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human JMJD6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39180-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for JMJD6

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Alternative Name: JMJD6

Background:

Background Information: JMJD6 is a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor.This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Jumonji domain containing 6

Alternative Symbols: PSR, PTDSR, PTDSR1

Protein Name: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

Molecular Weight: 46kDa

Gene ID: 23210

NCBI Accession: NP_055982

UniProt: Q6NYC1