PHF21A antibody (N-Term)

Catalog No. ABIN2781018

This Rabbit Polyclonal antibody specifically detects PHF21A in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Dog, Guinea Pig and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for PHF21A antibody (N-Term) (ABIN2781018)

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF21A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHF21A Antibody

Binding Specificity: N-Term

Sequence: MELQTLQEAL KVEIQVHQKL VAQMKQDPQN ADLKKQLHEL QAKITALSEK

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PHF21A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF21A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 634 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PHF21A antibody (ABIN2781018)

Hailesellasse Sene, Porter, Palidwor, Perez-Iratxeta, Muro, Campbell, Rudnicki, Andrade-Navarro: "Gene function in early mouse embryonic stem cell differentiation." in: BMC genomics, Vol. 8, pp. 85, (2007) (PubMed).

Target Details for PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Alternative Name: PHF21A

Background: PHF21A (BHC80) is a component of a BRAF35/histone deacetylase complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS). BHC80 is a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC, see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM].
Alias Symbols: BHC80, BM-006, KIAA1696
Protein Interaction Partner: KRT40, BANP, NUP62, ZYX, TRAF1, FHL3, HDAC2, HDAC1, HIST3H3, HMG20B, ELAVL1, SUMO2, HIST2H3C, ESCO2, KDM1A, TAF10, RCOR1, LPXN, GTF2I,
Protein Size: 634

Molecular Weight: 70 kDa

Gene ID: 51317

NCBI Accession: NM_016621, NP_057705

Pathways: Feeding Behaviour