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PHF21A antibody

PHF21A Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7262134
  • Target See all PHF21A Antibodies
    PHF21A (PHD Finger Protein 21A (PHF21A))
    Reactivity
    • 48
    • 14
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 45
    • 3
    Rabbit
    Clonality
    • 46
    • 2
    Polyclonal
    Conjugate
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PHF21A antibody is un-conjugated
    Application
    • 30
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PHF21A (NP_001095272.1).
    Isotype
    IgG
    Top Product
    Discover our top product PHF21A Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PHF21A (PHD Finger Protein 21A (PHF21A))
    Alternative Name
    PHF21A (PHF21A Products)
    Synonyms
    PHF21A antibody, im:7138823 antibody, si:dkey-23n7.9 antibody, BHC80 antibody, RGD1560612 antibody, 80kDa antibody, Bhc antibody, Bhc80 antibody, D030065N23Rik antibody, PFTF1 antibody, fj98d03 antibody, phf21a antibody, wu:fj98d03 antibody, PHD finger protein 21A antibody, PHD finger protein 21Aa antibody, PHD finger protein 21Ab antibody, PHF21A antibody, phf21aa antibody, pf21a antibody, phf21a antibody, LOC100549929 antibody, Phf21a antibody, phf21ab antibody
    Background
    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
    Molecular Weight

    Observed_MW: 70-80 kDa

    Calculated_MW: 70 kDa/74 kDa

    Gene ID
    51317
    UniProt
    Q96BD5
    Pathways
    Feeding Behaviour
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