Rabenosyn 5 antibody (N-Term)

Catalog No. ABIN501833

The Rabbit Polyclonal anti-Rabenosyn 5 antibody is suitable to detect Rabenosyn 5 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for Rabenosyn 5 antibody (N-Term) (ABIN501833)

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rabenosyn 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Rabenosyn 5 Antibody

Binding Specificity: N-Term

Purpose: RBSN Antibody - N-terminal region

Sequence: MASLDDPGEV REGFLCPLCL KDLQSFYQLH SHYEEEHSGE DRDVKGQIKS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ZFYVE20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZFYVE20

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39547-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Rabenosyn 5

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Alternative Name: RBSN

Background:

Background Information: This gene encodes a protein that belongs to the FYVE zinc finger family of proteins. The encoded protein interacts with Ras-related proteins that regulate membrane trafficking. A missense mutation in this gene is associated with a defect in the early endocytic pathway. Alternative splicing results in multiple transcript variants.

Gene Name: rabenosyn, RAB effector

Alternative Symbols: ZFYVE20, Rabenosyn-5

Protein Name: rabenosyn-5

Molecular Weight: 89kDa

Gene ID: 64145

NCBI Accession: NP_071735

UniProt: Q9H1K0

Pathways: Toll-Like Receptors Cascades