UBE2J2 antibody (C-Term)

Catalog No. ABIN2781244

Product Details anti-UBE2J2 Antibody

Target: UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2J2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GIQLLNGHAP GAVPNLAGLQ QANRHHGLLG GALANLFVIV GFAAFAYTVK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against UBE2J2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UBE2J2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 275 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBE2J2

Target: UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))

Alternative Name: UBE2J2 (UBE2J2 Products)

Synonyms: NCUBE-2 antibody, NCUBE2 antibody, PRO2121 antibody, 1200007B18Rik antibody, 2400008G19Rik antibody, 5730472G04Rik antibody, AL022923 antibody, Ubc6 antibody, Ubc6p antibody, zgc:162164 antibody, ubiquitin conjugating enzyme E2 J2 antibody, ubiquitin-conjugating enzyme E2J 2 antibody, ubiquitin-conjugating enzyme E2, J2 antibody, ubiquitin-conjugating enzyme E2 J2 antibody, ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast) antibody, ubiquitin conjugating enzyme E2 J2 L homeolog antibody, UBE2J2 antibody, Ube2j2 antibody, LOC5574000 antibody, CpipJ_CPIJ008956 antibody, ube2j2 antibody, uce2 antibody, ube2j2.L antibody, LOC100067387 antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2J2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: NCUBE2, PRO2121, NCUBE-2
Protein Interaction Partner: UBE2J2, UBC, ITCH, HERC4, ATP13A2, NEDD4L, WWP2, PARK2, MGRN1, RNF10, TRIM25, XIAP, UBE2G2,
Protein Size: 275

Molecular Weight: 30 kDa

Gene ID: 118424

NCBI Accession: NM_194315, NP_919296

UniProt: Q8N2K1