Deltex Homolog 3 antibody (C-Term)

Catalog No. ABIN2781281

The Rabbit Polyclonal anti-Deltex Homolog 3 antibody is suitable to detect Deltex Homolog 3 in samples from Human, Mouse, Cow, Rat, Horse, Pig, Rabbit, Dog, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Deltex Homolog 3 antibody (C-Term) (ABIN2781281)

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Reactivity: Human, Mouse, Cow, Rat, Horse, Pig, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deltex Homolog 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Deltex Homolog 3 Antibody

Binding Specificity: C-Term

Purpose: Dtx3 Antibody - C-terminal region

Sequence: YEKYGTIVIQ YVFPPGVQGA EHPNPGVRYP GTTRVAYLPD CPEGNKVLTL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Dtx3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43465-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Deltex Homolog 3

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Alternative Name: Dtx3

Background:

Background Information: Dtx3 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Dtx3 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Dtx3 functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Gene Name: Deltex 3 homolog (Drosophila)

Alternative Symbols: mg310, Deltex3

Protein Name: Probable E3 ubiquitin-protein ligase DTX3

Molecular Weight: 38kDa

Gene ID: 80904

NCBI Accession: NP_109639

UniProt: Q80V91

Pathways: Notch Signaling