TRIM54 antibody (N-Term)
Quick Overview for TRIM54 antibody (N-Term) (ABIN2781289)
Target
See all TRIM54 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- NFTVGFKPLL GDAHSMDNLE KQLICPICLE MFSKPVVILP CQHNLCRKCA
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against TRIM54. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM54
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 400 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRIM54 (Tripartite Motif Containing 54 (TRIM54))
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Alternative Name
- TRIM54
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Background
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TRIM54 contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MURF, MURF-3, RNF30, muRF3
Protein Interaction Partner: KRT6A, CCDC146, TSHZ3, TRIM54, EXOSC5, LIN37, NGLY1, RCOR3, TBC1D22B, RBM41, CCDC87, WDYHV1, C1orf109, ING3, DCUN1D1, MBD3, SPG21, VPS28, CHCHD2, RABGEF1, CYTH4, INPP5J, OSTF1, CCDC28A, ARFIP2, KDM1A, SNF8, MID2, FARS2, DNAL4, THOC1, EPM2AIP1, ELMO1, UTP1
Protein Size: 400 -
Molecular Weight
- 45 kDa
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Gene ID
- 57159
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NCBI Accession
- NM_032546, NP_115935
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UniProt
- Q9BYV2
Target
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