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ADH4 antibody (Middle Region)

ADH4 Reactivity: Human, Rat, Cow, Pig, Dog, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781328
  • Target See all ADH4 Antibodies
    ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))
    Binding Specificity
    • 8
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Rat, Cow, Pig, Dog, Rabbit
    Host
    • 31
    • 5
    Rabbit
    Clonality
    • 34
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADH4 antibody is un-conjugated
    Application
    • 29
    • 18
    • 18
    • 13
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    NSEKFVKAKA LGATDCLNPR DLHKPIQEVI IELTKGGVDF ALDCAGGSET
    Predicted Reactivity
    Cow: 86%, Dog: 86%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against ADH4. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ADH4
    Top Product
    Discover our top product ADH4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 380 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

  • Target
    ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))
    Alternative Name
    ADH4 (ADH4 Products)
    Synonyms
    ADH-2 antibody, Adh2 antibody, ADH-1 antibody, Ac1002 antibody, alcohol dehydrogenase 4 (class II), pi polypeptide antibody, alcohol dehydrogenase Adh4 antibody, ADH4 antibody, adh4 antibody, Adh4 antibody
    Background
    ADH4, class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole.This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
    Alias Symbols: ADH-2
    Protein Interaction Partner: UBC, RPL35, YWHAE, APP,
    Protein Size: 380
    Molecular Weight
    42 kDa
    Gene ID
    127
    NCBI Accession
    NM_000670, NP_000661
    UniProt
    P08319
    Pathways
    Transition Metal Ion Homeostasis
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