ABCA2 antibody (N-Term)

Catalog No. ABIN2781503

This Rabbit Polyclonal antibody specifically detects ABCA2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for ABCA2 antibody (N-Term) (ABIN2781503)

Target: ABCA2 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABCA2 Antibody

Binding Specificity: N-Term

Purpose: ABCA2 Antibody - N-terminal region

Sequence: ILPVMQSLCP DGQRDEFGFL QYANSTVTQL LERLDRVVEE GNLFDPARPS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ABCA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human ABCA2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43639-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABCA2

Target: ABCA2 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2))

Alternative Name: ABCA2

Background:

Background Information: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: ATP binding cassette subfamily A member 2

Alternative Symbols: ABC2, IDPOGSA

Protein Name: ATP-binding cassette sub-family A member 2

Molecular Weight: 108kDa

Gene ID: 20

NCBI Accession: NP_001597

UniProt: Q9BZC7