RAD50 antibody (N-Term)

Catalog No. ABIN2781516

The Rabbit Polyclonal anti-RAD50 antibody is suitable to detect RAD50 in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for RAD50 antibody (N-Term) (ABIN2781516)

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD50 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAD50 Antibody

Binding Specificity: N-Term

Sequence: SILGVRSFGI EDKDKQIITF FSPLTILVGP NGAGKTTIIE CLKYICTGDF

Specificity: 100 % homologous to both isoforms.

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RAD50. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RAD50

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAD50

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Alternative Name: RAD50

Background: The function of this protein remains unknown.
Protein Interaction Partner: BRCA1, ATRX, UBC, MDM2, PASK, RPA3, RPA2, RPA1, EED, RNF2, FBXO6, PAN2, UL29, WHSC1, MDC1, RNF8, RBL2, RINT1, TERF2, NBN, MRE11A, TERF2IP, NCSTN, NOP56, HNRNPR, Nfe2l2, DCLRE1C, TFAP4, SIRT7, HNRNPA1, SKP2, SUMO2, SMARCAD1, TOPBP1, RBBP8, BARD1, EBNA-LP,
Protein Size: 551

Molecular Weight: 60 kDa

Gene ID: 10111

UniProt: Q92878

Pathways: DNA Damage Repair, Protein targeting to Nucleus