ABCA5 antibody (C-Term)

Catalog No. ABIN2781525

The Rabbit Polyclonal anti-ABCA5 antibody (ABIN2781525) specifically detects ABCA5 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit and Horse samples.

Quick Overview for ABCA5 antibody (C-Term) (ABIN2781525)

Target: ABCA5 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 5 (ABCA5))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ABCA5 Antibody

Binding Specificity: C-Term

Purpose: ABCA5 Antibody - C-terminal region

Sequence: HKEYDDKKDF LLSRKVKKVA TKYISFCVKK GEILGLLGPN GAGKSTIINI

Predicted Reactivity: Cow: 79%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ABCA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ABCA5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43688-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABCA5

Target: ABCA5 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 5 (ABCA5))

Alternative Name: ABCA5

Background:

Background Information: The membrane-associated protein ABCA5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA5 is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.

Gene Name: ATP-binding cassette, sub-family A (ABC1), member 5

Alternative Symbols: HTC3, ABC13, EST90625

Protein Name: ATP-binding cassette sub-family A member 5

Molecular Weight: 186kDa

Gene ID: 23461

NCBI Accession: NP_061142

UniProt: Q8WWZ7