CYBA antibody (Middle Region)

Catalog No. ABIN2781765

The Rabbit Polyclonal anti-CYBA antibody (ABIN2781765) specifically detects CYBA in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Pig, Dog, Horse, Cow, Rabbit and Sheep samples.

Quick Overview for CYBA antibody (Middle Region) (ABIN2781765)

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Reactivity: Human, Mouse, Rat, Pig, Dog, Horse, Cow, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYBA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CYBA Antibody

Binding Specificity: Middle Region

Sequence: TILGTACLAI ASGIYLLAAV RGEQWTPIEP KPRERPQIGG TIKQPPSNPP

Predicted Reactivity: Cow: 93%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CYBA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYBA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 195 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYBA

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Alternative Name: CYBA

Background: Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated
Alias Symbols: p22-PHOX
Protein Interaction Partner: RBPMS, PSMA3, UPF2, RCHY1, UBC, MDFI, CPT1A, NCF1, VHL, RAC1, NCF4, CYBB, NOX1, NCF2,
Protein Size: 195

Molecular Weight: 21 kDa

Gene ID: 1535

NCBI Accession: NM_000101, NP_000092

UniProt: P13498

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis