Tyrosinase-Related Protein 1 antibody (N-Term)

Catalog No. ABIN2781813

The Rabbit Polyclonal anti-Tyrosinase-Related Protein 1 antibody has been validated for WB. It is suitable to detect Tyrosinase-Related Protein 1 in samples from Human, Mouse, Rat, Dog, Goat, Horse, Rabbit, Sheep, Cow, Guinea Pig and Pig.

Quick Overview for Tyrosinase-Related Protein 1 antibody (N-Term) (ABIN2781813)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reactivity: Human, Mouse, Rat, Dog, Goat, Horse, Rabbit, Sheep, Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosinase-Related Protein 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tyrosinase-Related Protein 1 Antibody

Binding Specificity: N-Term

Sequence: AKRTTHPLFV IATRRSEEIL GPDGNTPQFE NISIYNYFVW THYYSVKKTF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against TYRP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TYRP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 537 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Alternative Name: TYRP1

Background: TYRP1 catalyses the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. It may regulate or influence the type of melanin synthesized.
Alias Symbols: CAS2, CATB, GP75, TRP, TYRP, b-PROTEIN
Protein Interaction Partner: RAB11A, TF, RAB5A, HSPA4, TYR, GIPC1,
Protein Size: 537

Molecular Weight: 59 kDa

Gene ID: 7306

NCBI Accession: NM_000550, NP_000541

UniProt: P17643