COMT antibody (Middle Region)

Catalog No. ABIN2781821

The Rabbit Polyclonal anti-COMT antibody is suitable to detect COMT in samples from Human, Rat, Mouse, Dog, Cow, Pig, Horse, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for COMT antibody (Middle Region) (ABIN2781821)

Target: COMT (Catechol-O-Methyltransferase (COMT))

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COMT Antibody

Binding Specificity: Middle Region

Sequence: PDCAAITQRM VDFAGVKDKV TLVVGASQDI IPQLKKKYDV DTLDMVFLDH

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against COMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COMT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 271 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COMT

Target: COMT (Catechol-O-Methyltransferase (COMT))

Alternative Name: COMT

Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathwa
Alias Symbols: -
Protein Interaction Partner: KRT40, TRIP13, UBC, KRT31, KRTAP5-9, CDC27, RNF2, FBXO6, vpr, FN1, VKORC1, VCP, RGS2, LITAF, XRN2, ACE,
Protein Size: 271

Molecular Weight: 30 kDa

Gene ID: 1312

NCBI Accession: NM_000754, NP_000745

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome