Osteoactivin antibody (N-Term)

Catalog No. ABIN2781895

The Rabbit Polyclonal anti-Osteoactivin antibody is suitable to detect Osteoactivin in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog and Pig. It has been validated for WB.

Quick Overview for Osteoactivin antibody (N-Term) (ABIN2781895)

Target: Osteoactivin (GPNMB)

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Osteoactivin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Osteoactivin Antibody

Binding Specificity: N-Term

Sequence: DGENGTGQSH HNVFPDGKPF PHHPGWRRWN FIYVFHTLGQ YFQKLGRCSV

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 572 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Osteoactivin

Target: Osteoactivin (GPNMB)

Alternative Name: GPNMB

Background: GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly me
Alias Symbols: HGFIN, NMB
Protein Interaction Partner: UBC, SMAD4, ITSN2,
Protein Size: 572

Molecular Weight: 62 kDa

Gene ID: 10457

NCBI Accession: NM_001005340, NP_001005340

UniProt: Q14956